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Research has shown GHK-Cu influences expression of over 4,000 human genes, stimulates collagen I, III and elastin synthesis, activates matrix metalloproteinases for extracellular matrix remodelling, supports angiogenesis through VEGF and FGF upregulation, and suppresses pro-inflammatory TNF- signalling

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MAGMA: generalized gene-set analysis of GWAS data

3 The SLC2A9 gene, which encodes the fructose/urate co-transporter GLUT9, has been implicated in the greater number of Mori and Pacific peoples living with gout (see: The burden of gout is more severe among Mori and Pacific peoples)